Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.46 |
| ▸ | SMARCA2 | P51531 | 5/20 | 0.46 |
| ▸ | SMARCA4 | P51532 | 4/20 | 0.46 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | TET3 | O43151 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | ASPH | Q12797 | 1/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.42 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10633345 | 0.90 | SRD5A2 (0.52) | TAS1R3TAS1R1TAS1R2PROKR1MAPT | |
| SCHEMBL4227036 | 0.90 | KMT2A (0.57) | KDM4EKDM6BKDM4AALDH1A1KDM5A | |
| SCHEMBL20892408 | 0.87 | LMNA (0.59) | RECQLTAS1R3TAS1R1TAS1R2SMARCA2 | |
| SCHEMBL20892726 | 0.87 | LMNA (0.55) | TAS1R3TAS1R1TAS1R2SMARCA2SMARCA4 | |
| SCHEMBL10633305 | 0.87 | LTA4H (0.59) | TAS1R3TAS1R1TAS1R2KDM4EKDM4A | |
| SCHEMBL3927686 | 0.87 | LMNA (0.42) | RECQLTAS1R3TAS1R1TAS1R2SMARCA2 | |
| SCHEMBL73194 | 0.84 | TAS1R3 (0.45) | RECQLTAS1R3TAS1R1TAS1R2SMARCA2 | |
| SCHEMBL14204663 | 0.84 | TAS1R3 (0.45) | RECQLTAS1R3TAS1R1TAS1R2SMARCA2 | |
| SCHEMBL40123 | 0.84 | KDM4C (0.61) | RECQLTAS1R3TAS1R1TAS1R2KDM4E | |
| SCHEMBL4736651 | 0.84 | HTT (0.41) | RECQLTAS1R3TAS1R1TAS1R2SMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101218232-A | Novel oxadiazole derivatives and their use as positive allosteric modulators of metabotropic glutamate receptors | ADDEX PHARMACEUTICALS SA (CH) | 2008-07-09 | — | — | CN | claimed |
| CN-116368128-A | Heterocyclic compounds as CBP/EP300 bromodomain inhibitors | 奥瑞基尼肿瘤有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-101370810-B | Diaza-spiro [4.5] decanes useful as pesticides | SYNGENTA PARTICIPATIONS AG (CH) | 2013-01-02 | — | — | CN | disclosed |
| CN-101370810-A | Diaza-spiro [4.5] decanes useful as pesticides | SYNGENTA PARTICIPATIONS AG (CH) | 2009-02-18 | — | — | CN | disclosed |
| CN-101218232-A | Novel oxadiazole derivatives and their use as positive allosteric modulators of metabotropic glutamate receptors | ADDEX PHARMACEUTICALS SA (CH) | 2008-07-09 | — | — | CN | disclosed |
| CN-100349895-C | Pyrrolopyridazine derivatives | ASTELLAS PHARMA INC (JP) | 2007-11-21 | — | — | CN | disclosed |
| CN-1759117-A | Pyrrolopyridazine derivatives | ASTELLAS PHARMA INC (JP) | 2006-04-12 | — | — | CN | disclosed |