Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7842017 | 1.00 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL7841011 | 0.94 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL7846158 | 0.94 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL7841022 | 0.91 | ESR1 (0.61) | PTGS2PTGS1 | |
| SCHEMBL7842507 | 0.91 | ESR1 (0.61) | PTGS2PTGS1 | |
| SCHEMBL7833104 | 0.90 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL7841893 | 0.90 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL7845665 | 0.89 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL7841885 | 0.89 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL7842756 | 0.89 | PTGS2 (0.66) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1125932-A2 | Substituted thiazoles for the treatment of inflammation | G.D. SEARLE & CO. (US) | 2001-08-22 | — | — | EP | disclosed |
| US-5668161-A | Substituted thiazoles for the treatment of inflammation | G.D. SEARLE & CO. (US) | 1997-09-16 | — | — | US | disclosed |