Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6805136 | 0.99 | ROCK1 (0.48) | ROCK1CSNK1A1CSNK1DCLK2CSNK1G1 | |
| SCHEMBL6809073 | 0.91 | CSNK1A1 (0.54) | ROCK1CSNK1A1CSNK1DCLK2CSNK1G1 | |
| SCHEMBL6804421 | 0.86 | MAPK14 (0.58) | CSNK1A1CSNK1DCLK2CSNK1G1MAPK14 | |
| SCHEMBL6805884 | 0.85 | GRM6 (0.49) | CSNK1A1CSNK1DCLK2CSNK1G1MAPK14 | |
| SCHEMBL6809510 | 0.84 | CSNK1A1 (0.50) | ROCK1CSNK1A1CSNK1DCLK2CSNK1G1 | |
| SCHEMBL7847013 | 0.83 | GRM6 (0.51) | CSNK1A1CSNK1DCLK2CSNK1G1RAB9A | |
| SCHEMBL6801978 | 0.83 | CSNK1A1 (0.44) | ROCK1CSNK1A1CSNK1DCLK2CSNK1G1 | |
| SCHEMBL7844049 | 0.83 | KIF11 (0.47) | CSNK1A1CSNK1DCLK2CSNK1G1RAB9A | |
| Hydrochloric Acid SCHEMBL6802046 | 0.82 | GRM6 (0.50) | CSNK1A1CSNK1DCLK2CSNK1G1RAB9A | |
| Hydrochloric Acid SCHEMBL6803318 | 0.82 | KIF11 (0.46) | CSNK1A1CSNK1DCLK2CSNK1G1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853083-B1 | Pyridylfuran and pyridylthiophene compounds and pharmaceutical use thereof | PFIZER (US) | 2001-09-12 | — | — | EP | claimed |