Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 10/20 | 0.39 |
| ▸ | CALML3 | P27482 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5833795 | 0.85 | MAOA (0.45) | MAOACALML3MAOBCYP3A4CYP2C19 | |
| SCHEMBL5834202 | 0.84 | MAOA (0.42) | MAOACALML3MAOBCYP3A4CYP2C19 | |
| SCHEMBL5834855 | 0.78 | MAOB (0.34) | MAOACALML3MAOBF10 | |
| Hydrochloric Acid SCHEMBL5833221 | 0.78 | MAOA (0.36) | MAOACALML3MAOBF10 | |
| SCHEMBL7107280 | 0.78 | MAOA (0.58) | MAOACALML3MAOBF10 | |
| SCHEMBL5833603 | 0.77 | MAOA (0.42) | MAOACALML3MAOBF10 | |
| SCHEMBL5833669 | 0.76 | MAOA (0.40) | MAOACALML3MAOBF10 | |
| Hydrochloric Acid SCHEMBL5834433 | 0.71 | MAOA (0.47) | MAOACALML3MAOB | |
| SCHEMBL13298877 | 0.71 | MAOA (0.47) | MAOACALML3MAOB | |
| SCHEMBL5834262 | 0.70 | MAOA (0.34) | MAOACALML3MAOBF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121358-A1 | HETEROCYCLYLAMINOMETHYLOXAZOLIDINONES AS ANTIBACTERIALS | AstraZeneca AB (SE) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000021960-A1 | HETEROCYCLYL AMINO METHYLOXA ZOLIDINONES AS ANTIBACTERIALS | ASTRAZENECA AB (SE) | 2000-04-20 | — | — | WO | disclosed |