Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814897 | 0.91 | MAPT (0.68) | MAPTMEN1KMT2APOLBTP53 | |
| SCHEMBL7938457 | 0.88 | MAPT (0.67) | MAPTMEN1KMT2APOLBTP53 | |
| SCHEMBL6672864 | 0.87 | MAPT (0.64) | MAPTMEN1KMT2ARXFP1 | |
| SCHEMBL6694734 | 0.85 | MAPT (0.64) | MAPTMEN1KMT2APOLBTP53 | |
| SCHEMBL6697128 | 0.85 | MAPT (0.63) | MAPTMEN1KMT2APOLBRXFP1 | |
| SCHEMBL6668589 | 0.85 | MAPT (0.61) | MAPTMEN1KMT2ATP53 | |
| SCHEMBL6693496 | 0.84 | MAPT (0.60) | MAPTMEN1KMT2APOLBTP53 | |
| SCHEMBL6700119 | 0.84 | MAPT (0.62) | MAPTMEN1KMT2ARXFP1 | |
| SCHEMBL6697958 | 0.84 | MAPT (0.60) | MAPTMEN1KMT2APOLBTP53 | |
| SCHEMBL6815376 | 0.83 | MEN1 (0.61) | MAPTMEN1KMT2ATP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140850-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| US-6248739-B1 | DNA POLYMERASE INHIBITORS EFFECTIVE AGAINST HERPESVIRUSES | PHARMACIA & UPJOHN COMPANY | 2001-06-19 | — | — | US | disclosed |
| WO-2000040561-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |