Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | CTSG | P08311 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004957 | 1.00 | CYP19A1 (0.43) | CYP19A1SIGMAR1RAB9AACEFAAH | |
| SCHEMBL7842649 | 1.00 | CYP19A1 (0.43) | CYP19A1SIGMAR1RAB9AACEFAAH | |
| SCHEMBL7004961 | 1.00 | CYP19A1 (0.43) | CYP19A1SIGMAR1RAB9AACEFAAH | |
| SCHEMBL7842654 | 1.00 | CYP19A1 (0.43) | CYP19A1SIGMAR1RAB9AACEFAAH | |
| SCHEMBL7003629 | 0.87 | CYP19A1 (0.56) | CYP19A1SIGMAR1ERN1 | |
| SCHEMBL7007402 | 0.82 | CYP19A1 (0.42) | CYP19A1SIGMAR1RAB9AACEFAAH | |
| SCHEMBL9542673 | 0.78 | SMN1; SMN2 (0.46) | RAB9ANPSR1 | |
| SCHEMBL9542681 | 0.78 | SMN1; SMN2 (0.46) | RAB9ANPSR1 | |
| SCHEMBL2380115 | 0.77 | HSD17B10 (0.40) | CHRM1NPSR1 | |
| SCHEMBL2380113 | 0.77 | HSD17B10 (0.40) | CHRM1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109811-A2 | PYRROLOBENZODIAZEPINES | Spirogen Limited (GB) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000012507-A2 | PYRROLOBENZODIAZEPINES | SPIROGEN LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |