Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.61 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.61 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | METAP1 | P53582 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.55 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CLK1 | P49759 | 4/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15561399 | 0.82 | CYP1A2 (0.70) | CYP1A2NPC1RAB9APIM1AKR1B1 | |
| SCHEMBL15561397 | 0.82 | CYP1A2 (0.70) | CYP1A2NPC1RAB9APIM1AKR1B1 | |
| SCHEMBL17693072 | 0.82 | CYP1A2 (0.70) | CYP1A2NPC1RAB9APIM1AKR1B1 | |
| SCHEMBL5753409 | 0.80 | CYP1A2 (0.67) | PABPC1APOBEC3AAPOBEC3GCYP1A2NPC1 | |
| SCHEMBL5753412 | 0.80 | CYP1A2 (0.67) | PABPC1APOBEC3AAPOBEC3GCYP1A2NPC1 | |
| SCHEMBL9177271 | 0.79 | CLK1 (0.63) | PABPC1APOBEC3AAPOBEC3GCYP1A2NPC1 | |
| SCHEMBL9177264 | 0.79 | CLK1 (0.63) | PABPC1APOBEC3AAPOBEC3GCYP1A2NPC1 | |
| SCHEMBL15421684 | 0.78 | PIM1 (0.62) | CYP1A2NPC1RAB9APIM1AKR1B1 | |
| SCHEMBL15421683 | 0.78 | PIM1 (0.62) | CYP1A2NPC1RAB9APIM1AKR1B1 | |
| SCHEMBL23633280 | 0.78 | CYP1A2 (0.86) | CYP1A2DYRK1ADYRK1BMAPTCLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686613-B1 | OZONIDE REDUCING AGENT | OTSUKA KAGAKU KK (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-5770729-A | SULFIDE COMPOUND WITH POLAR SUBSTITUENTS, FORMATION OF SULFOXIDE, MILD CONDITIONS, SAFE, NONPOLLUTING | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1998-06-23 | — | — | US | disclosed |
| EP-0686613-A1 | OZONIDE REDUCING AGENT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |