Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 5/20 | 0.64 |
| ▸ | SRC | P12931 | 5/20 | 0.64 |
| ▸ | TEK | Q02763 | 3/20 | 0.64 |
| ▸ | BTK | Q06187 | 11/20 | 0.58 |
| ▸ | HCK | P08631 | 7/20 | 0.53 |
| ▸ | FLT3 | P36888 | 4/20 | 0.53 |
| ▸ | FYN | P06241 | 2/20 | 0.51 |
| ▸ | LYN | P07948 | 2/20 | 0.51 |
| ▸ | YES1 | P07947 | 1/20 | 0.51 |
| ▸ | FGR | P09769 | 1/20 | 0.51 |
| ▸ | TEC | P42680 | 1/20 | 0.51 |
| ▸ | TXK | P42681 | 1/20 | 0.51 |
| ▸ | BLK | P51451 | 1/20 | 0.51 |
| ▸ | BMX | P51813 | 1/20 | 0.51 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RGS12 | O14924 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6461718 | 0.92 | LCK (0.62) | LCKSRCTEKBTKHCK | |
| SCHEMBL6459603 | 0.92 | LCK (0.61) | LCKSRCTEKBTKHCK | |
| SCHEMBL6461408 | 0.88 | LCK (0.60) | LCKSRCTEKBTKHCK | |
| SCHEMBL6463938 | 0.87 | LCK (0.59) | LCKSRCTEKBTKHCK | |
| SCHEMBL7855243 | 0.86 | SRC (0.68) | LCKSRCTEKBTKHCK | |
| SCHEMBL7852098 | 0.86 | SRC (0.67) | LCKSRCTEKBTKHCK | |
| SCHEMBL7851979 | 0.86 | LCK (0.65) | LCKSRCTEKBTKHCK | |
| SCHEMBL6461162 | 0.85 | LCK (0.59) | LCKSRCTEKBTKHCK | |
| SCHEMBL6458751 | 0.85 | LCK (0.59) | LCKSRCTEKBTKHCK | |
| SCHEMBL7853262 | 0.85 | SRC (0.66) | LCKSRCTEKBTKHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114053-A1 | PYRROLOPYRIMIDINES AS PROTEIN KINASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000017203-A1 | PYRROLOPYRIMIDINES AS PROTEIN KINASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-30 | — | — | WO | disclosed |