Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 7/20 | 0.66 |
| ▸ | LCK | P06239 | 6/20 | 0.66 |
| ▸ | TEK | Q02763 | 5/20 | 0.66 |
| ▸ | BTK | Q06187 | 8/20 | 0.54 |
| ▸ | HCK | P08631 | 6/20 | 0.51 |
| ▸ | FLT3 | P36888 | 4/20 | 0.51 |
| ▸ | KDR | P35968 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RGS12 | O14924 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | LYN | P07948 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468012 | 0.92 | LCK (0.63) | SRCLCKTEKBTKHCK | |
| SCHEMBL7855243 | 0.88 | SRC (0.68) | SRCLCKTEKBTKHCK | |
| SCHEMBL7852098 | 0.87 | SRC (0.67) | SRCLCKTEKBTKHCK | |
| SCHEMBL7851979 | 0.86 | LCK (0.65) | SRCLCKTEKBTKHCK | |
| SCHEMBL7842853 | 0.85 | LCK (0.64) | SRCLCKTEKBTKHCK | |
| SCHEMBL7853877 | 0.84 | SRC (0.68) | SRCLCKTEKBTKHCK | |
| SCHEMBL7853089 | 0.84 | LCK (0.62) | SRCLCKTEKBTKHCK | |
| SCHEMBL7852451 | 0.83 | LCK (0.66) | SRCLCKTEKBTKHCK | |
| SCHEMBL7850708 | 0.83 | SRC (0.66) | SRCLCKTEKBTKHCK | |
| SCHEMBL6462888 | 0.82 | SRC (0.70) | SRCLCKTEKBTKHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114053-A1 | PYRROLOPYRIMIDINES AS PROTEIN KINASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000017203-A1 | PYRROLOPYRIMIDINES AS PROTEIN KINASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-30 | — | — | WO | disclosed |