Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.49 |
| ▸ | MAOA | P21397 | 9/20 | 0.46 |
| ▸ | CALML3 | P27482 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SDHA | P31040 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14898022 | 0.85 | MAOB (0.56) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL8440576 | 0.85 | MAOB (0.47) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL8111378 | 0.83 | CALML3 (0.61) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL5337288 | 0.83 | MAOB (0.50) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL8111373 | 0.83 | CALML3 (0.61) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL5337295 | 0.83 | MAOB (0.50) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL5231103 | 0.83 | MAOB (0.49) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL13939826 | 0.83 | MAOA (0.49) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL5834806 | 0.83 | MAOB (0.48) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL5234526 | 0.83 | MAOB (0.48) | MAOBMAOACALML3LMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807112-B1 | HETERO-AROMATIC RING SUBSTITUTED PHENYLOXAZOLIDINONE ANTIMICROBIALS | UPJOHN CO (US) | 2001-09-05 | — | — | EP | disclosed |
| US-6124334-A | A BACTERICIDE TREATING INFECTIONS CAUSED BY GRAM-POSITIVE AEROBIC BACTERIA SUCH AS STAPHYLOCOCCUS, STREPTOCOCCUS AND ENTEROCOCCUS AS WELL AS ANAEROBIC ORGANISMS SUCH AS BACTEROIDES AND CLOSTRIDIUM AND MYCOBACTERIDIUM | PHARMACIA & UPJOHN COMPANY (US) | 2000-09-26 | — | — | US | disclosed |
| WO-1996023788-A1 | HETERO-AROMATIC RING SUBSTITUTED PHENYLOXAZOLIDINONE ANTIMICROBIALS | PHARMACIA + UPJOHN COMPANY (US) | 1996-08-08 | — | — | WO | disclosed |