Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 14/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836009 | 0.90 | ADRB2 (0.56) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| Hydrochloric Acid SCHEMBL7842895 | 0.89 | ADRB2 (0.55) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| Hydrochloric Acid SCHEMBL7852828 | 0.83 | ADRB2 (0.70) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL7837137 | 0.83 | ADRB2 (0.62) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL7838985 | 0.81 | ADRB2 (0.67) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL7840332 | 0.81 | ADRB2 (0.77) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL7839917 | 0.81 | ADRB2 (0.72) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL7836704 | 0.81 | ADRB2 (0.77) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL7828804 | 0.80 | ADRB2 (0.62) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL8880819 | 0.80 | ADRB2 (0.58) | ADRB2ABCB11ADRB1DRD2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558677-B1 | BIOLOGICALLY ACTIVE AMINES | ASTRAZENECA AB (SE) | 2001-08-16 | — | — | EP | disclosed |
| US-5648370-A | 7-(2-aminoethyl) benzothiazolones | ASTRA PHARMACEUTICALS LIMITED (GB) | 1997-07-15 | — | — | US | disclosed |
| WO-1992008708-A1 | BIOLOGICALLY ACTIVE AMINES | FISONS PLC (GB) | 1992-05-29 | — | — | WO | disclosed |