Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.65 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.65 |
| ▸ | IGF1R | P08069 | 1/20 | 0.63 |
| ▸ | CDK4 | P11802 | 1/20 | 0.61 |
| ▸ | CCND1 | P24385 | 1/20 | 0.61 |
| ▸ | AANAT | Q16613 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7853851 | 0.90 | MAPT (0.66) | GFERMEN1KMT2AMAPTGAA | |
| SCHEMBL7852879 | 0.90 | GFER (0.84) | GFERMEN1KMT2AMAPTGAA | |
| SCHEMBL12009647 | 0.89 | GFER (1.00) | GFERMEN1KMT2AMAPTGAA | |
| SCHEMBL7850949 | 0.88 | GFER (0.80) | GFERMEN1KMT2AMAPTGAA | |
| SCHEMBL7846928 | 0.88 | GFER (0.80) | GFERMEN1KMT2AMAPTGAA | |
| P-Toluenesulfonamide SCHEMBL29272927 | 0.87 | ALDH1A1 (0.68) | GFERMEN1KMT2AMAPTGAA | |
| P-Toluenesulfonamide SCHEMBL29272949 | 0.87 | ALDH1A1 (0.68) | GFERMEN1KMT2AMAPTGAA | |
| SCHEMBL7677886 | 0.87 | MEN1 (0.84) | GFERMEN1KMT2AMAPTGAA | |
| SCHEMBL9117842 | 0.85 | MEN1 (0.76) | GFERMEN1KMT2AMAPTMTNR1A | |
| SCHEMBL9303476 | 0.84 | MEN1 (0.71) | GFERMEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140914-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037462-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2000-06-29 | — | — | WO | disclosed |