SCHEMBL7843420

SCHEMBL7843420

O=S(=O)(CCCl)CCNc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.39
TYMS P04818 1/20 0.39
CA1 P00915 6/20 0.38
CA2 P00918 6/20 0.38
LMNA P02545 1/20 0.37
ALDH1A1 P00352 2/20 0.36
TSHR P16473 2/20 0.36
NT5E P21589 1/20 0.36
CA12 O43570 3/20 0.35
CA9 Q16790 3/20 0.35
TIMP3 P35625 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
SNCA P37840 1/20 0.33
PTPRA P18433 1/20 0.33
PTPRB P23467 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7756142 0.91 ALDH1A1 (0.39) PRMT1TYMSCA1CA2LMNA
SCHEMBL9816419 0.85 TYMS (0.39) TYMSCA1CA2LMNAALDH1A1
SCHEMBL7840209 0.82 CA1 (0.41) CA1CA2LMNAALDH1A1TSHR
SCHEMBL7839536 0.81 CA1 (0.40) CA1CA2ALDH1A1CA12CA9
SCHEMBL6473072 0.81 TYMS (0.37) TYMSCA1CA2LMNAALDH1A1
SCHEMBL6560645 0.80 APP (0.39) PRMT1CA1CA2CA12CA9
SCHEMBL7837359 0.80 ALDH1A1 (0.47) CA1CA2ALDH1A1CA12CA9
SCHEMBL10383695 0.78 PRSS1 (0.39) CA1CA2ALDH1A1CA12CA9
Hydrochloric Acid SCHEMBL9661181 0.77 PRSS1 (0.41) CA1CA2ALDH1A1CA12CA9
SCHEMBL6561058 0.77 CA1 (0.33) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0675172-B1 Water-solable azo compounds, process for their preparation and their use as dyestuffs DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-04-11 EP disclosed
US-5770709-A BRILLIANT COLOR SHADES, GOOD FASTNESS DURING USE AT HIGH DEGREE OF FIXING DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) 1998-06-23 US disclosed
US-5539088-A PROVIDE DYEINGS IN BRILLIANT SHADES WITH GOOD FASTNESS PROPERTIES AND HIGH DEGREE OF FIXATION HOECHST AKTIENGESELLSCHAFT (DE) 1996-07-23 US disclosed
EP-0675172-A2 Water-solable azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-04 EP disclosed
EP-0382111-B1 Copper complex-formazane compounds, process for their preparation and their use as dyestuffs HOECHST AG (DE) 1994-06-08 EP disclosed
US-5015731-A For fibers such as wool and cellulose HOECHST AKTIENGESELLSCHAFT (DE) 1991-05-14 US disclosed
US-4908436-A Reactive dyes CIBA-GEIGY CORPORATION (US) 1990-03-13 US disclosed
US-4841028-A FOR COLD PAD-BATCH PROCESS HUNTSMAN INTERNATIONAL LLC 1989-06-20 US disclosed
US-4709018-A COLORFAST CIBA-GEIGY CORPORATION (US) 1987-11-24 US disclosed