Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 2/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10077165 | 0.94 | HDAC1 (0.36) | CCNE2CCNE1CDK2CKS1BSKP1 | |
| SCHEMBL430210 | 0.92 | CCNE2 (0.38) | CCNE2CCNE1CDK2CKS1BSKP1 | |
| SCHEMBL6803680 | 0.90 | TDP1 (0.40) | CCNE2CCNE1CDK2CKS1BSKP1 | |
| SCHEMBL434638 | 0.86 | TLR7 (0.36) | CCNE2CCNE1CDK2CKS1BSKP1 | |
| SCHEMBL13037056 | 0.86 | CCNE2 (0.37) | CCNE2CCNE1CDK2CKS1BSKP1 | |
| SCHEMBL430139 | 0.85 | CKS1B (0.36) | CCNE2CCNE1CDK2CKS1BSKP1 | |
| SCHEMBL458786 | 0.85 | MEN1 (0.38) | CCNE2CCNE1CDK2CKS1BSKP1 | |
| SCHEMBL10047121 | 0.85 | HDAC1 (0.39) | CCNE2CCNE1CDK2HDAC1HDAC2 | |
| SCHEMBL7852849 | 0.84 | CDK5 (0.41) | CCNE2CCNE1CDK2CKS1BSKP1 | |
| SCHEMBL431129 | 0.84 | CCNE2 (0.40) | CCNE2CCNE1CDK2MCL1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1085020-A1 | Synthesis of modified diaminopurines and their incorporation into oligomers | DAKO A/S (DK) | 2001-03-21 | — | — | EP | disclosed |