Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL430139 | 0.89 | CKS1B (0.36) | MEN1KMT2ACKS1BSKP1SKP2 | |
| SCHEMBL7263683 | 0.88 | L3MBTL1 (0.36) | MEN1TSHRKMT2ACKS1BSKP1 | |
| SCHEMBL6046933 | 0.86 | KDM4E (0.39) | MEN1TSHRKMT2ACKS1BSKP1 | |
| SCHEMBL7843680 | 0.85 | CCNE2 (0.39) | CKS1BSKP1SKP2SYKCCNE2 | |
| SCHEMBL430210 | 0.85 | CCNE2 (0.38) | MEN1KMT2ACKS1BSKP1SKP2 | |
| SCHEMBL3669585 | 0.84 | CKS1B (0.34) | MEN1KMT2ACKS1BSKP1SKP2 | |
| SCHEMBL6803680 | 0.84 | TDP1 (0.40) | CKS1BSKP1SKP2SYKCCNE2 | |
| SCHEMBL459081 | 0.83 | MAPT (0.37) | MEN1KMT2ACKS1BSKP1SKP2 | |
| SCHEMBL7913306 | 0.83 | POLB (0.38) | MEN1TSHRKMT2ATK1 | |
| SCHEMBL10077228 | 0.82 | SYK (0.36) | MEN1TSHRKMT2ACKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230135545-A1 | BIOMIMETIC G-QUARTET COMPOUNDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-05-04 | — | — | US | disclosed |
| EP-4126865-A1 | BIOMIMETIC G-QUARTET COMPOUNDS | Centre national de la recherche scientifique (FR) | 2023-02-08 | — | — | EP | disclosed |
| US-20130231480-A1 | SEQUENCE SPECIFIC DOUBLE-STRANDED DNA/RNA BINDING COMPOUNDS AND USES THEREOF | GENEARREST LTD (IL) | 2013-09-05 | — | — | US | disclosed |
| EP-2596102-A2 | SEQUENCE SPECIFIC DOUBLE-STRANDED DNA/RNA BINDING COMPOUNDS AND USES THEREOF | GeneArrest Ltd (IL) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012011114-A2 | SEQUENCE SPECIFIC DOUBLE-STRANDED DNA/RNA BINDING COMPOUNDS AND USES THEREOF | GENEARREST LTD (IL) | 2012-01-26 | — | — | WO | disclosed |
| US-20100284959-A1 | SEQUENCE SPECIFIC DOUBLE-STRANDED DNA/RNA BINDING COMPOUNDS AND USES THEREOF | GENE ARREST LTD. (IL) | 2010-11-11 | — | — | US | disclosed |
| US-20040009899-A1 | Reducing the level of an RNA or polypeptide expressed by a mutant allele of a gene that causes a dominant disorder in a mammal by administering a polyamide nucleic acid oligomer that is heterozygous for such a mutant allele | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2004-01-15 | — | — | US | disclosed |
| US-6548651-B1 | Conjugating cationic peptides to peptide nucleic acids; microbiocides | PANTHECO A/S (DK) | 2003-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100284959-A1 | SEQUENCE SPECIFIC DOUBLE-STRANDED DNA/RNA BINDING COMPOUNDS AND USES THEREOF | POLRMT, POLM, SNRPE | MEN1 4592/4885TSHR 2598/4885KMT2A 2479/4885 |
| US-20230135545-A1 | BIOMIMETIC G-QUARTET COMPOUNDS | PYM1, B4GALT1, NGLY1 | MEN1 58/4885TSHR 3477/4885KMT2A 1478/4885 |
| US-20130231480-A1 | SEQUENCE SPECIFIC DOUBLE-STRANDED DNA/RNA BINDING COMPOUNDS AND USES THEREOF | POLM, POLRMT, DDB1 | MEN1 4509/4885TSHR 2534/4885KMT2A 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.