Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 12/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8382438 | 1.00 | DNM1 (0.55) | DNM1TSHRTHRBMEN1KMT2A | |
| SCHEMBL10758036 | 1.00 | DNM1 (0.55) | DNM1TSHRTHRBMEN1KMT2A | |
| SCHEMBL10757502 | 1.00 | DNM1 (0.55) | DNM1TSHRTHRBMEN1KMT2A | |
| SCHEMBL1795959 | 1.00 | DNM1 (0.55) | DNM1TSHRTHRBMEN1KMT2A | |
| SCHEMBL20969262 | 1.00 | DNM1 (0.55) | DNM1TSHRTHRBMEN1KMT2A | |
| SCHEMBL11179206 | 1.00 | DNM1 (0.55) | DNM1TSHRTHRBMEN1KMT2A | |
| SCHEMBL1793039 | 1.00 | DNM1 (0.55) | DNM1TSHRTHRBMEN1KMT2A | |
| SCHEMBL7756737 | 1.00 | DNM1 (0.55) | DNM1TSHRTHRBMEN1KMT2A | |
| SCHEMBL1795960 | 1.00 | DNM1 (0.55) | DNM1TSHRTHRBMEN1KMT2A | |
| SCHEMBL5484071 | 1.00 | DNM1 (0.55) | DNM1TSHRTHRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1141140-A1 | NAPHTHALENEHYDRAZAMIMIDES AND PERYLENEHYDRAZAMIMIDES | Ciba SC Holding AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040657-A1 | NAPHTHALENEHYDRAZAMIMIDES AND PERYLENEHYDRAZAMIMIDES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-07-13 | — | — | WO | disclosed |
| US-4397965-A | HYDRAZINE DERIVATIVE BLOWING AGENT | UNIROYAL, INC. (US) | 1983-08-09 | — | — | US | disclosed |
| EP-0083173-A1 | Expandable and curable polyester composition and method for making same | UNIROYAL, INC. (US) | 1983-07-06 | — | — | EP | disclosed |