Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 14/20 | 0.57 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15559787 | 0.85 | ELANE (0.52) | ELANELRRK2KDM4DIMPDH2 | |
| SCHEMBL1822112 | 0.84 | ELANE (0.54) | ELANELRRK2KDM4DIMPDH2CDK2 | |
| SCHEMBL15559790 | 0.81 | ELANE (0.48) | ELANELRRK2KDM4DIMPDH2CFTR | |
| SCHEMBL16464569 | 0.79 | ELANE (0.61) | ELANELRRK2KDM4DIMPDH2CDK2 | |
| SCHEMBL21140258 | 0.77 | SLC6A2 (0.40) | ELANEKDM4D | |
| SCHEMBL12146949 | 0.76 | ELANE (0.57) | ELANELRRK2KDM4DIMPDH2CDK2 | |
| SCHEMBL20674541 | 0.76 | ELANE (0.61) | ELANELRRK2KDM4DCDK2 | |
| SCHEMBL28049881 | 0.76 | ELANE (0.57) | ELANELRRK2KDM4DIMPDH2CDK2 | |
| SCHEMBL28822922 | 0.76 | ELANE (0.57) | ELANELRRK2KDM4DIMPDH2CDK2 | |
| SCHEMBL19678808 | 0.76 | KDM4E (0.41) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149098-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF 7-AZAINDOLYL-3-CARBOXYLIC ACID | Dompé S.P.A. (IT) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000029411-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF 7-AZAINDOLYL-3-CARBOXYLIC ACID | DOMPE' SPA (IT) | 2000-05-25 | — | — | WO | disclosed |