Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 1.00 |
| ▸ | CA2 | P00918 | 3/20 | 1.00 |
| ▸ | CA9 | Q16790 | 3/20 | 1.00 |
| ▸ | CA7 | P43166 | 2/20 | 1.00 |
| ▸ | CA12 | O43570 | 1/20 | 1.00 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17858266 | 0.90 | CA12 (0.82) | CA1CA2CA9CA7CA12 | |
| SCHEMBL1817195 | 0.86 | CA12 (0.76) | CA1CA2CA9CA7CA12 | |
| SCHEMBL31513336 | 0.83 | CA12 (0.71) | CA1CA2CA9CA7CA12 | |
| SCHEMBL14058862 | 0.82 | CA12 (0.69) | CA1CA2CA9CA7CA12 | |
| SCHEMBL2081068 | 0.80 | CA12 (0.67) | CA1CA2CA9CA7CA12 | |
| SCHEMBL2227782 | 0.79 | CA1 (0.65) | CA1CA2CA9CA7CA12 | |
| SCHEMBL8801961 | 0.79 | CA1 (0.64) | CA1CA2CA9CA7CA12 | |
| SCHEMBL14058976 | 0.78 | CA1 (0.64) | CA1CA2CA9CA7CA12 | |
| SCHEMBL30770403 | 0.77 | ESR1 (0.65) | CA1CA2CA9CA7CA12 | |
| SCHEMBL20681402 | 0.77 | ESR1 (0.65) | CA1CA2CA9CA7CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015142001-A2 | COMPOUND HAVING CARDIOTONIC ACTIVITY AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING HEART FAILURE, CONTAINING SAME | 충남대학교산학협력단 | 2015-09-24 | — | — | WO | disclosed |
| EP-1021437-B1 | ARYLSULFONYLIMIDAZOLONE DERIVATIVES AS AN ANTITUMOR AGENT | DONG WHA PHARM IND CO LTD (KR) | 2001-11-14 | — | — | EP | disclosed |
| EP-1021437-A1 | ARYLSULFONYLIMIDAZOLONE DERIVATIVES AS AN ANTITUMOR AGENT | DONG WHA PHARMACEUTICAL INDUSTRIAL CO. LTD. (KR) | 2000-07-26 | — | — | EP | disclosed |
| US-5932742-A | CHEMICAL INTERMEDIATE TO ACTIVE ANTITUMOR AGENT | DONG WHA PHARM. IND. CO., LTD. (KR) | 1999-08-03 | — | — | US | disclosed |
| US-5929103-A | ANTICARCINOGENIC AGENTS | DONG WHA PHARM. IND. CO., LTD. (KR) | 1999-07-27 | — | — | US | disclosed |
| WO-1998007719-A1 | ARYLSULFONYLIMIDAZOLONE DERIVATIVES AS AN ANTITUMOR AGENT | DONG WHA PHARM. IND. CO., LTD. (KR) | 1998-02-26 | — | — | WO | disclosed |