Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1192955 | 0.97 | LMNA (0.45) | LMNAALDH1A1CA12CA1CA2 | |
| SCHEMBL19757269 | 0.94 | LMNA (0.43) | LMNAALDH1A1CA12CA1CA2 | |
| SCHEMBL15082605 | 0.94 | LMNA (0.43) | LMNAALDH1A1CA12CA1CA2 | |
| SCHEMBL25468178 | 0.94 | LMNA (0.43) | LMNAALDH1A1CA12CA1CA2 | |
| SCHEMBL12346238 | 0.94 | LMNA (0.43) | LMNAALDH1A1CA12CA1CA2 | |
| SCHEMBL25468179 | 0.94 | LMNA (0.43) | LMNAALDH1A1CA12CA1CA2 | |
| SCHEMBL15082606 | 0.94 | LMNA (0.43) | LMNAALDH1A1CA12CA1CA2 | |
| SCHEMBL26841027 | 0.94 | LMNA (0.43) | LMNAALDH1A1CA12CA1CA2 | |
| SCHEMBL23696800 | 0.91 | LMNA (0.41) | LMNAALDH1A1CA12CA1CA2 | |
| SCHEMBL25468180 | 0.91 | LMNA (0.41) | LMNAALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098883-A4 | PROCESS FOR PREPARING HETEROCYCLIC COMPOUNDS | LILLY CO ELI (US) | 2001-11-14 | — | — | EP | disclosed |
| EP-1098883-A1 | PROCESS FOR PREPARING HETEROCYCLIC COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-05-16 | — | — | EP | disclosed |
| WO-1998054151-A1 | PROCESS FOR PREPARING HETEROCYCLIC COMPOUNDS | ELI LILLY AND COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |