Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854062 | 0.78 | KDM4E (0.36) | GAAKDM4EGLAMEN1KMT2A | |
| SCHEMBL7854440 | 0.78 | GAA (0.34) | GAAKDM4EGLAMEN1KMT2A | |
| SCHEMBL7854016 | 0.77 | SRD5A1 (0.41) | GAAKDM4EMEN1KMT2APOLB | |
| SCHEMBL7853444 | 0.74 | CYP19A1 (0.42) | POLBHPGDGABRA1GABRB2PTPN1 | |
| SCHEMBL7851986 | 0.74 | PTPN1 (0.43) | PTPN1 | |
| SCHEMBL12559791 | 0.73 | BRD4 (0.37) | GAAKDM4EGLAMEN1KMT2A | |
| SCHEMBL7855978 | 0.71 | CYP19A1 (0.45) | POLBHPGDGABRA1GABRB2PTPN1 | |
| SCHEMBL429180 | 0.71 | BRD4 (0.43) | BRD4ALDH1A1 | |
| SCHEMBL8660070 | 0.71 | KDM4E (0.34) | GAAKDM4EGLAMEN1KMT2A | |
| SCHEMBL426989 | 0.71 | NPC1 (0.42) | KDM4EGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1084330-C | Cydic amide derivatives | OTSUKA PHARMA CO LTD (JP) | 2002-05-08 | — | — | CN | disclosed |
| EP-0719258-B1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5786367-A | OXYGEN SCAVENGERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| CN-1130377-A | Cyclic amide derivatives | OTSUKA PHARMA CO LTD (JP) | 1996-09-04 | — | — | CN | disclosed |