SCHEMBL7851986

SCHEMBL7851986

C=CCc1cc2c(c(CC=C)c1OC1CCCCO1)CCC(=O)N2

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7844527 0.74 GAA (0.34) PTPN1
SCHEMBL7853241 0.72 PTPN1 (0.36) PTPN1
SCHEMBL6579955 0.69 PTPN1 (0.40) PTPN1
SCHEMBL6577406 0.69 PTPN1 (0.40) PTPN1
SCHEMBL12559791 0.67 BRD4 (0.37)
SCHEMBL429180 0.63 BRD4 (0.43)
SCHEMBL7241509 0.63 KMT2A (0.45) PTPN1
SCHEMBL7854016 0.63 SRD5A1 (0.41)
SCHEMBL27531226 0.63 PTPN1 (0.45) PTPN1
SCHEMBL10468109 0.63 PTPN1 (0.48) PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1084330-C Cydic amide derivatives OTSUKA PHARMA CO LTD (JP) 2002-05-08 CN disclosed
EP-0719258-B1 CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS OTSUKA PHARMA CO LTD (JP) 2001-10-31 EP disclosed
US-5786367-A OXYGEN SCAVENGERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1998-07-28 US disclosed
CN-1130377-A Cyclic amide derivatives OTSUKA PHARMA CO LTD (JP) 1996-09-04 CN disclosed