Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A6 | Q3KNW5 | 3/20 | 0.72 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.72 |
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.72 |
| ▸ | GPR27 | Q9NS67 | 8/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.57 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | METAP2 | P50579 | 2/20 | 0.51 |
| ▸ | ACLY | P53396 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6754585 | 0.94 | SLC10A6 (0.81) | SLC10A6SLC10A2SLC10A1GPR27KDM4E | |
| SCHEMBL6760783 | 0.89 | SLC10A6 (0.74) | SLC10A6SLC10A2SLC10A1GPR27KDM4E | |
| SCHEMBL491625 | 0.88 | SLC10A6 (0.72) | SLC10A6SLC10A2SLC10A1GPR27KDM4E | |
| SCHEMBL5115455 | 0.88 | SLC10A6 (0.88) | SLC10A6SLC10A2SLC10A1GPR27KDM4E | |
| SCHEMBL491711 | 0.88 | SLC10A6 (0.72) | SLC10A6SLC10A2SLC10A1GPR27KDM4E | |
| SCHEMBL492157 | 0.88 | SLC10A6 (0.72) | SLC10A6SLC10A2SLC10A1GPR27KDM4E | |
| SCHEMBL5126855 | 0.87 | SLC10A6 (0.71) | SLC10A6SLC10A2SLC10A1GPR27KDM4E | |
| SCHEMBL6862400 | 0.87 | SLC10A6 (0.71) | SLC10A6SLC10A2SLC10A1GPR27KDM4E | |
| SCHEMBL5126186 | 0.86 | SLC10A6 (0.69) | SLC10A6SLC10A2SLC10A1GPR27KDM4E | |
| SCHEMBL5126790 | 0.86 | SLC10A6 (0.69) | SLC10A6SLC10A2SLC10A1GPR27KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1125932-A2 | Substituted thiazoles for the treatment of inflammation | G.D. SEARLE & CO. (US) | 2001-08-22 | — | — | EP | disclosed |
| EP-1095015-A2 | SULFONYLAMINO CARBOXYLIC ACID N-ARYLAMIDES AS GUANYLATE CYCLASE ACTIVATORS | Aventis Pharma Deutschland GmbH (DE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000002850-A2 | SULFONYLAMINO CARBOXYLIC ACID N-ARYLAMIDES AS GUANYLATE CYCLASE ACTIVATORS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-01-20 | — | — | WO | disclosed |