Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 10/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9395564 | 0.91 | — | — | |
| SCHEMBL3042461 | 0.84 | SMPD1 (0.31) | SMPD1CES1FDPSGGPS1 | |
| SCHEMBL17491820 | 0.76 | SMPD1 (0.40) | SMPD1CES1FDPSGGPS1 | |
| SCHEMBL11661453 | 0.74 | FDPS (0.36) | SMPD1FDPSGGPS1 | |
| SCHEMBL8759725 | 0.71 | — | — | |
| SCHEMBL9034719 | 0.70 | FDPS (0.33) | FDPSGGPS1 | |
| SCHEMBL570532 | 0.70 | TSHR (0.30) | — | |
| SCHEMBL27686626 | 0.70 | TSHR (0.36) | SMPD1FDPSGGPS1 | |
| SCHEMBL14844470 | 0.69 | ESR1 (0.38) | CES1FDPSGGPS1 | |
| SCHEMBL21086309 | 0.69 | ESR1 (0.38) | FDPSGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105376-A1 | OXINDOLE DERIVATIVES AS GROWTH HORMONE RELEASERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000010975-A1 | OXINDOLE DERIVATIVES AS GROWTH HORMONE RELEASERS | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2000-03-02 | — | — | WO | disclosed |