⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7502244 | 0.85 | KCNH2 (0.43) | — | |
| SCHEMBL7494525 | 0.85 | KCNH2 (0.34) | — | |
| SCHEMBL7502250 | 0.83 | KCNH2 (0.36) | — | |
| SCHEMBL7842251 | 0.80 | STAT3 (0.36) | — | |
| SCHEMBL7995325 | 0.80 | STAT3 (0.36) | — | |
| SCHEMBL7836504 | 0.78 | KCNH2 (0.46) | — | |
| SCHEMBL7494366 | 0.78 | KCNH2 (0.46) | — | |
| SCHEMBL7836509 | 0.78 | KCNH2 (0.46) | — | |
| SCHEMBL7846924 | 0.78 | KCNH2 (0.46) | — | |
| SCHEMBL7846922 | 0.78 | KCNH2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010036941-A1 | Use of 7-(1-aminomethyl-2-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)-quinolonecarboxylic acid and -naphthyridonecarboxylic acid derivatives for the therapy of Helicobacter pylori infections and associated gastroduodenal disorders | PETERSEN UWE (DE) | 2001-11-01 | — | — | US | disclosed |
| US-6288081-B1 | Use of 7-(1-aminomethyl-2-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)-quinolone carboxylic acid and naphthyridone carboxylic acid derivatives for treating Helicobacter pylori infections and the gastroduodenal diseases associated therewith | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-11 | — | — | US | disclosed |