Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7842251 | 1.00 | STAT3 (0.36) | STAT3KCNH2SCN5AADRB2 | |
| SCHEMBL7494525 | 0.90 | KCNH2 (0.34) | KCNH2SCN5A | |
| Hydrochloric Acid SCHEMBL7847229 | 0.89 | KCNH2 (0.34) | KCNH2SCN5A | |
| SCHEMBL7844634 | 0.80 | — | — | |
| Bicarbonate SCHEMBL7496529 | 0.80 | KCNH2 (0.36) | KCNH2 | |
| Bicarbonate SCHEMBL7496066 | 0.79 | KCNH2 (0.35) | KCNH2 | |
| SCHEMBL7856565 | 0.79 | KCNH2 (0.34) | KCNH2 | |
| SCHEMBL7844447 | 0.77 | STAT3 (0.48) | STAT3ADRB2 | |
| SCHEMBL7492130 | 0.76 | KCNH2 (0.53) | KCNH2 | |
| SCHEMBL7495552 | 0.76 | KCNH2 (0.42) | STAT3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288081-B1 | Use of 7-(1-aminomethyl-2-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)-quinolone carboxylic acid and naphthyridone carboxylic acid derivatives for treating Helicobacter pylori infections and the gastroduodenal diseases associated therewith | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-11 | — | — | US | disclosed |