Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 3/20 | 0.36 |
| ▸ | PARP1 | P09874 | 11/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.35 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7844298 | 0.91 | TIPARP (0.36) | TIPARPPARP1TNK2TNK1GPR119 | |
| SCHEMBL7844293 | 0.91 | TIPARP (0.36) | TIPARPPARP1TNK2TNK1GPR119 | |
| SCHEMBL6986552 | 0.85 | PARP1 (0.40) | TIPARPPARP1TNK2TNK1GPR119 | |
| SCHEMBL7832492 | 0.85 | PARP1 (0.40) | TIPARPPARP1TNK2TNK1GPR119 | |
| SCHEMBL6608314 | 0.84 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL6608489 | 0.79 | PANK3 (0.38) | PARP1TNK2TNK1KCNH2PANK3 | |
| SCHEMBL7849828 | 0.79 | PANK3 (0.41) | PARP1TNK2TNK1KCNH2PANK3 | |
| SCHEMBL6610427 | 0.79 | PANK3 (0.39) | PARP1TNK2TNK1KCNH2PANK3 | |
| SCHEMBL6609310 | 0.74 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL6607807 | 0.74 | KCNH2 (0.44) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082322-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AstraZeneca AB (SE) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999064416-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 1999-12-16 | — | — | WO | disclosed |