Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 12/20 | 0.40 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.39 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.38 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832492 | 1.00 | PARP1 (0.40) | PARP1PANK3TNK2TNK1GPR119 | |
| SCHEMBL7844298 | 0.85 | TIPARP (0.36) | PARP1PANK3TNK2TNK1GPR119 | |
| SCHEMBL7844768 | 0.85 | TIPARP (0.36) | PARP1PANK3TNK2TNK1GPR119 | |
| SCHEMBL7844293 | 0.85 | TIPARP (0.36) | PARP1PANK3TNK2TNK1GPR119 | |
| SCHEMBL6607491 | 0.82 | CALML3 (0.51) | — | |
| SCHEMBL13344776 | 0.80 | F10 (0.45) | — | |
| SCHEMBL7849828 | 0.75 | PANK3 (0.41) | PARP1PANK3TNK2TNK1 | |
| SCHEMBL6608489 | 0.73 | PANK3 (0.38) | PARP1PANK3TNK2TNK1 | |
| SCHEMBL7081325 | 0.73 | L3MBTL1 (0.44) | GPR119USP30 | |
| SCHEMBL7081327 | 0.73 | L3MBTL1 (0.44) | GPR119USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357122-A2 | Oxazolidinone compounds and pharmaceutical compositions containing them | AstraZeneca AB (SE) | 2003-10-29 | — | — | EP | disclosed |
| EP-1082323-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AstraZeneca UK Limited (GB) | 2001-03-14 | — | — | EP | disclosed |
| EP-1082322-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AstraZeneca AB (SE) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999064416-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 1999-12-16 | — | — | WO | disclosed |
| WO-1999064417-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 1999-12-16 | — | — | WO | disclosed |