Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.72 |
| ▸ | DRD2 | P14416 | 2/20 | 0.60 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2095198 | 0.98 | HTR2C (0.70) | HTR2CDRD2GID4ADRA1AHTR2A | |
| Ammonia Solution, Strong SCHEMBL19664329 | 0.98 | HTR2C (0.70) | HTR2CDRD2GID4ADRA1AHTR2A | |
| SCHEMBL1515075 | 0.96 | HTR2C (0.72) | HTR2CDRD2GID4ADRA1AHTR2A | |
| SCHEMBL1515134 | 0.92 | HTR2C (0.77) | HTR2CDRD2GID4ADRA1AHTR2A | |
| SCHEMBL30997824 | 0.92 | HTR2C (0.77) | HTR2CDRD2GID4ADRA1AHTR2A | |
| Methyl Alcohol SCHEMBL8097139 | 0.89 | HTR2C (0.72) | HTR2CDRD2GID4ADRA1AHTR2A | |
| SCHEMBL11258120 | 0.85 | HTR2C (0.68) | HTR2CDRD2ADRA1AHTR2A | |
| SCHEMBL3679174 | 0.85 | HTR2C (0.68) | HTR2CDRD2GID4ADRA1AHTR2A | |
| SCHEMBL28695004 | 0.85 | HTR2C (0.68) | HTR2CDRD2GID4ADRA1AHTR2A | |
| SCHEMBL3316532 | 0.84 | HTR2C (0.66) | HTR2CDRD2GID4ADRA1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064262-A1 | SUBSTITUTED ISOINDOLONES AND THEIR USE AS CYCLIC GMP MODULATORS IN MEDICAMENTS | Aventis Pharma Deutschland GmbH (DE) | 2001-01-03 | — | — | EP | disclosed |
| WO-1999042444-A1 | SUBSTITUTED ISOINDOLONES AND THEIR USE AS CYCLIC GMP MODULATORS IN MEDICAMENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-08-26 | — | — | WO | disclosed |
| US-4837301-A | FROM ALKALI MTEAL SULFIDES AND AROMATIC DIHALOGEN COMPOUNDS; IMPROVED CORROSION RESISTANCE | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-06 | — | — | US | disclosed |
| EP-0275007-A2 | Process for the preparation of highly molecular, optionally branched polyarylene sulfides | BAYER AG (DE) | 1988-07-20 | — | — | EP | disclosed |