SCHEMBL7844883

SCHEMBL7844883

Sc1nc(Oc2ccccc2)nc(Oc2ccccc2)n1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAX8 Q06710 1/20 0.53
LTA4H P09960 3/20 0.48
TSHR P16473 1/20 0.48
KMT2A Q03164 4/20 0.46
MEN1 O00255 3/20 0.46
ALDH1A1 P00352 2/20 0.46
POLB P06746 2/20 0.43
GLA P06280 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HPGD P15428 1/20 0.42
KDM4E B2RXH2 1/20 0.42
MAPT P10636 1/20 0.42
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
CA9 Q16790 3/20 0.41
MAPK1 P28482 1/20 0.40
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39
GAA P10253 1/20 0.39
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3389739 0.95 PAX8 (0.48) PAX8LTA4HTSHRKMT2AMEN1
SCHEMBL1006428 0.88 PAX8 (0.63) PAX8LTA4HTSHRKMT2AMEN1
SCHEMBL24262518 0.85 KMT2A (0.61) PAX8LTA4HTSHRKMT2AMEN1
SCHEMBL26373155 0.79 PAX8 (0.55) PAX8LTA4HTSHRKMT2AMEN1
SCHEMBL2232138 0.77 PAX8 (0.58) PAX8LTA4HTSHRKMT2AMEN1
SCHEMBL22724736 0.77 SMN1; SMN2 (0.54) PAX8LTA4HTSHRKMT2AMEN1
SCHEMBL5198118 0.77 KMT2A (0.64) PAX8LTA4HTSHRKMT2AMEN1
SCHEMBL49317 0.77 PAX8 (0.53) PAX8LTA4HTSHRKMT2AMEN1
SCHEMBL24124452 0.77 SMN1; SMN2 (0.54) PAX8LTA4HTSHRKMT2AMEN1
SCHEMBL7844878 0.77 PAX8 (0.53) PAX8LTA4HTSHRKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0710882-B1 Colour photographic material AGFA GEVAERT (BE) 2001-01-03 EP disclosed
US-5573892-A Use of Yellow couplers of the indolo [3,2-B] guinoline type in a colo ur photographic development process AGFA-GEVAERT AG (DE) 1996-11-12 US disclosed
EP-0710882-A1 New yellow couplers of indolo 3,2-b quinolin-type and their use in a colour photographic developing process Agfa-Gevaert AG (DE) 1996-05-08 EP disclosed
EP-0438148-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-07-24 EP disclosed