Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTPA | P49638 | 4/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7844737 | 0.93 | TTPA (0.39) | TTPAPTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL7839838 | 0.86 | TTPA (0.44) | TTPAPTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL7825046 | 0.84 | TTPA (0.56) | TTPAPTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL7834764 | 0.83 | TTPA (0.41) | TTPAPTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL7836919 | 0.82 | PTGS1 (0.57) | TTPAPTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL7838645 | 0.81 | TTPA (0.45) | TTPAPTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL7833394 | 0.80 | TTPA (0.46) | TTPAPTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL8520297 | 0.79 | PTGS1 (0.57) | TTPAPTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL7836663 | 0.79 | TTPA (0.53) | TTPAPTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL7837725 | 0.78 | TTPA (0.43) | TTPAPTGS1PTGS2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844245-B1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-05-09 | — | — | EP | disclosed |
| US-5889045-A | ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 1999-03-30 | — | — | US | disclosed |
| EP-0844245-A1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-05-27 | — | — | EP | disclosed |