Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 6/20 | 0.64 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.56 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921496 | 0.92 | MTNR1B (0.72) | MTNR1BMTNR1AMEN1KMT2AMAPK1 | |
| SCHEMBL30741237 | 0.89 | KMT2A (0.71) | MTNR1BMTNR1AMEN1KMT2AMAPK1 | |
| SCHEMBL2112594 | 0.89 | KMT2A (0.71) | MTNR1BMTNR1AMEN1KMT2AMAPK1 | |
| SCHEMBL9479511 | 0.89 | MTNR1B (0.68) | MTNR1BMTNR1AMEN1KMT2AMAPK1 | |
| SCHEMBL30741242 | 0.89 | KMT2A (0.71) | MTNR1BMTNR1AMEN1KMT2AMAPK1 | |
| SCHEMBL9479608 | 0.89 | MTNR1B (0.68) | MTNR1BMTNR1AMEN1KMT2AMAPK1 | |
| SCHEMBL1085867 | 0.88 | MEN1 (0.71) | MTNR1BMTNR1AMEN1KMT2AMAPK1 | |
| SCHEMBL1921418 | 0.87 | MTNR1B (0.66) | MTNR1BMTNR1AMEN1KMT2AMAPK1 | |
| SCHEMBL30080139 | 0.86 | MTNR1B (0.65) | MTNR1BMTNR1AMEN1KMT2AMAPK1 | |
| SCHEMBL917608 | 0.86 | MTNR1B (0.65) | MTNR1BMTNR1AMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802173-B1 | Process for producing heterocylic aromatic amine or arylamine | TOSOH CORP (JP) | 2001-12-19 | — | — | EP | disclosed |
| US-5929281-A | REACTING A HETROCYCLIC AROMATIC HALIDE WITH AN AMINE COMPOUND IN PRESENCE OF A BASE USING A TRI-TERT-BUTYLPHOSPHINE AND PALLADIUM COMPOUND CATALYST TO FORM HETEROCYCLIC AROMATIC AMINE COMPOUNDS | TOSOH CORPORATION (JP) | 1999-07-27 | — | — | US | disclosed |
| EP-0802173-A1 | Process for producing heterocylic aromatic amine or arylamine | Tosoh Corporation (JP) | 1997-10-22 | — | — | EP | disclosed |