Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | CASP6 | P55212 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11133610 | 0.84 | HPGD (0.62) | KMT2AMEN1CASP6GAAHPGD | |
| SCHEMBL6328308 | 0.78 | HPGD (0.74) | KMT2AMEN1CASP6GAAHPGD | |
| SCHEMBL6772536 | 0.77 | HPGD (0.68) | KMT2AMEN1CASP6GAAHPGD | |
| SCHEMBL7845228 | 0.76 | HPGD (0.57) | KMT2AMEN1CASP6GAAHPGD | |
| SCHEMBL3027278 | 0.75 | CYP3A4 (0.50) | KMT2AMEN1CASP6GAAHPGD | |
| SCHEMBL29651988 | 0.74 | GAA (0.59) | KMT2AMEN1CASP6GAAHPGD | |
| SCHEMBL2982634 | 0.74 | GAA (0.59) | KMT2AMEN1CASP6GAAHPGD | |
| SCHEMBL4692980 | 0.74 | HPGD (0.69) | KMT2AMEN1CASP6GAAHPGD | |
| SCHEMBL11563108 | 0.74 | HPGD (0.54) | KMT2AMEN1CASP6GAAHPGD | |
| SCHEMBL10562313 | 0.73 | KMT2A (0.77) | KMT2AMEN1CASP6GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105376-A1 | OXINDOLE DERIVATIVES AS GROWTH HORMONE RELEASERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000010975-A1 | OXINDOLE DERIVATIVES AS GROWTH HORMONE RELEASERS | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2000-03-02 | — | — | WO | disclosed |