Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.56 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675954 | 0.82 | HPGD (0.69) | HPGDMAPTHTTRECQLALDH1A1 | |
| SCHEMBL7847712 | 0.79 | HPGD (0.65) | HPGDNPSR1MAPTHTTRECQL | |
| SCHEMBL6969241 | 0.77 | MAPT (0.72) | HPGDNPSR1MAPTHTTRECQL | |
| SCHEMBL6206331 | 0.77 | HPGD (0.63) | HPGDNPSR1MAPTHTTALDH1A1 | |
| SCHEMBL7853054 | 0.77 | HPGD (0.62) | HPGDNPSR1MAPTHTTRECQL | |
| SCHEMBL3602531 | 0.76 | HPGD (0.61) | HPGDMAPTHTTRECQLALDH1A1 | |
| SCHEMBL7677886 | 0.76 | MEN1 (0.84) | MAPTALDH1A1NPC1RAB9AGAA | |
| SCHEMBL7852692 | 0.75 | HPGD (0.60) | HPGDNPSR1MAPTHTTRECQL | |
| SCHEMBL13973308 | 0.75 | MAPT (0.74) | HPGDMAPTHTTRECQLALDH1A1 | |
| SCHEMBL7851490 | 0.75 | HTT (0.88) | HPGDMAPTHTTRECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140914-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037462-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2000-06-29 | — | — | WO | disclosed |