Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 15/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850071 | 0.90 | ADA (0.56) | ADA | |
| SCHEMBL7847452 | 0.90 | ADA (0.67) | ADAGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL7848923 | 0.86 | CYP1A2 (0.41) | ADAHTR1D | |
| SCHEMBL6938856 | 0.83 | ADA (0.80) | ADA | |
| SCHEMBL7848399 | 0.81 | ADA (0.54) | ADAHTR1DHTR1B | |
| SCHEMBL7836767 | 0.79 | ADA (0.68) | ADA | |
| SCHEMBL6936319 | 0.77 | ADA (0.80) | ADA | |
| SCHEMBL6941256 | 0.77 | ADA (0.80) | ADA | |
| SCHEMBL7846263 | 0.77 | ADA (0.48) | ADAHTR1DHTR1B | |
| SCHEMBL6938448 | 0.75 | ADA (0.79) | ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161429-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055155-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-09-21 | — | — | WO | disclosed |