Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 9/20 | 0.48 |
| ▸ | HTR1B | P28222 | 9/20 | 0.37 |
| ▸ | HTR1A | P08908 | 8/20 | 0.37 |
| ▸ | HTR1D | P28221 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848925 | 0.87 | ADA (0.44) | ADA | |
| SCHEMBL7847893 | 0.85 | ADA (0.43) | ADAHTR1BHTR1AHTR1DMAPT | |
| SCHEMBL7848399 | 0.84 | ADA (0.54) | ADAHTR1BHTR1AHTR1DMAPT | |
| SCHEMBL7836809 | 0.81 | ADA (0.43) | ADAHTR2A | |
| SCHEMBL7850190 | 0.79 | ADA (0.43) | ADACYP2C19 | |
| SCHEMBL7847420 | 0.78 | ADA (0.49) | ADAHTR1DMAPTKDM4EMEN1 | |
| SCHEMBL7846259 | 0.77 | ADA (0.55) | ADAHTR1BHTR1D | |
| SCHEMBL6938856 | 0.77 | ADA (0.80) | ADA | |
| SCHEMBL7850266 | 0.76 | PTPRA (0.41) | ADAHTR1AHTR1DMAPTCYP2C19 | |
| SCHEMBL7847454 | 0.75 | ADA (0.41) | ADAHTR1BHTR1AHTR1DMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161429-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055155-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-09-21 | — | — | WO | disclosed |