Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.56 |
| ▸ | MEN1 | O00255 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | POLB | P06746 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | GFER | P55789 | 4/20 | 0.56 |
| ▸ | GLA | P06280 | 4/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | RECQL | P46063 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784359 | 0.89 | POLB (0.47) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1925827 | 0.82 | MAPT (0.76) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8990129 | 0.81 | MAPT (0.73) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL393991 | 0.72 | ALDH1A1 (0.56) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6625448 | 0.71 | ALDH1A1 (0.56) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL12109509 | 0.70 | ALDH1A1 (0.58) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7783498 | 0.69 | PRKCI (0.49) | MAPTALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL1925825 | 0.69 | KDM4E (0.57) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL21788566 | 0.69 | MEN1 (0.86) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4230805 | 0.68 | ALDH1A1 (0.56) | MAPTALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137647-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034268-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |