Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 17/20 | 0.71 |
| ▸ | RARG | P13631 | 10/20 | 0.71 |
| ▸ | RARB | P10826 | 8/20 | 0.71 |
| ▸ | RXRG | P48443 | 10/20 | 0.41 |
| ▸ | RXRB | P28702 | 8/20 | 0.41 |
| ▸ | RARA | P10276 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846457 | 1.00 | RXRA (0.71) | RXRARARGRARBRXRGRXRB | |
| SCHEMBL8197360 | 0.98 | RXRA (0.74) | RXRARARGRARBRXRGRXRB | |
| SCHEMBL8366216 | 0.98 | RXRA (0.74) | RXRARARGRARBRXRGRXRB | |
| SCHEMBL8196021 | 0.89 | RXRA (0.76) | RXRARARGRARBRXRGRXRB | |
| SCHEMBL8196019 | 0.89 | RXRA (0.76) | RXRARARGRARBRXRGRXRB | |
| SCHEMBL4879231 | 0.86 | RXRA (0.96) | RXRARARGRARBRXRGRXRB | |
| SCHEMBL4879243 | 0.86 | RXRA (0.96) | RXRARARGRARBRXRGRXRB | |
| SCHEMBL8189608 | 0.85 | RXRA (0.73) | RXRARARGRARBRXRGRXRB | |
| SCHEMBL8359437 | 0.85 | RXRA (0.94) | RXRARARGRARBRXRGRXRB | |
| SCHEMBL8674942 | 0.85 | RXRA (0.94) | RXRARARGRARBRXRGRXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997455-A1 | Restricted 9-cis retenoids | American Cyanamid Company (US) | 2000-05-03 | — | — | EP | claimed |
| US-5968908-A | Restricted 9-cis retinoids | AMERICAN CYANAMID COMPANY (US) | 1999-10-19 | — | — | US | claimed |
| EP-0718285-A2 | Restricted 9-cis-retinoids | American Cyanamid Company (US) | 1996-06-26 | — | — | EP | claimed |
| JP-8291094-A | — | — | None | — | — | JP | disclosed |
| EP-0718285-B1 | Restricted 9-cis-retinoids | AMERICAN CYANAMID CO (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-0997455-A1 | Restricted 9-cis retenoids | American Cyanamid Company (US) | 2000-05-03 | — | — | EP | disclosed |
| US-5968908-A | Restricted 9-cis retinoids | AMERICAN CYANAMID COMPANY (US) | 1999-10-19 | — | — | US | disclosed |
| JP-H08291094-A | RESTRICTED 9-CIS-RETINOID | AMERICAN CYANAMID CO | 1996-11-05 | — | — | JP | disclosed |
| EP-0718285-A2 | Restricted 9-cis-retinoids | American Cyanamid Company (US) | 1996-06-26 | — | — | EP | disclosed |