Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.47 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | SUV39H2 | Q9H5I1 | 5/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.40 |
| ▸ | ITGAL | P20701 | 3/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847483 | 0.88 | SYK (0.46) | SYKCKS1BSKP1SKP2PDE10A | |
| SCHEMBL7239787 | 0.86 | SYK (0.56) | SYKCKS1BSKP1SKP2PDE10A | |
| SCHEMBL7239864 | 0.82 | SYK (0.41) | SYKCKS1BSKP1SKP2 | |
| SCHEMBL7239861 | 0.78 | GPBAR1 (0.40) | SYKCKS1BSKP1SKP2 | |
| SCHEMBL7239866 | 0.78 | GPBAR1 (0.40) | SYKCKS1BSKP1SKP2 | |
| SCHEMBL4278748 | 0.77 | GPBAR1 (0.47) | SYKITGB2ICAM1ITGALCCNC | |
| SCHEMBL29849700 | 0.76 | SUV39H2 (0.52) | SYKCKS1BSKP1SKP2PDE10A | |
| SCHEMBL1351789 | 0.74 | SYK (0.64) | SYKCKS1BSKP1SKP2PDE10A | |
| SCHEMBL1351791 | 0.74 | SYK (0.64) | SYKCKS1BSKP1SKP2PDE10A | |
| SCHEMBL20051576 | 0.73 | USP30 (0.58) | SYKCKS1BSKP1SKP2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157022-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000049015-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-24 | — | — | WO | disclosed |