Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NHERF1 | O14745 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667519 | 0.87 | NHERF1 (0.52) | NHERF1MAPTRXFP1POLBADORA2A | |
| SCHEMBL6670300 | 0.85 | NHERF1 (0.50) | NHERF1MAPTRXFP1POLBADORA2A | |
| SCHEMBL7834823 | 0.83 | NHERF1 (0.60) | NHERF1MAPTPOLBADORA2AADORA1 | |
| SCHEMBL7845700 | 0.78 | NHERF1 (0.61) | NHERF1MAPTPOLBADORA2AADORA1 | |
| SCHEMBL6204818 | 0.77 | NHERF1 (0.59) | NHERF1MAPTRXFP1POLBADORA2A | |
| SCHEMBL6670721 | 0.77 | NHERF1 (0.55) | NHERF1MAPTPOLBADORA2AADORA1 | |
| SCHEMBL6818435 | 0.76 | POLB (0.67) | NHERF1POLBADORA2AADORA1SMN1; SMN2 | |
| SCHEMBL6204128 | 0.76 | NHERF1 (0.68) | NHERF1MAPTRXFP1POLBADORA2A | |
| SCHEMBL6230550 | 0.76 | NHERF1 (0.68) | NHERF1MAPTPOLBADORA2AADORA1 | |
| SCHEMBL6205197 | 0.76 | POLB (0.61) | NHERF1MAPTPOLBSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140850-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040561-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |