Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 8/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 12/20 | 0.39 |
| ▸ | BCL2 | P10415 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850442 | 0.90 | ADA (0.49) | ADAMCL1 | |
| SCHEMBL7836409 | 0.88 | ADA (0.58) | ADAMCL1BCL2 | |
| SCHEMBL7848120 | 0.83 | ADA (0.35) | ADAMCL1 | |
| SCHEMBL7846603 | 0.81 | ADA (0.54) | ADA | |
| SCHEMBL7850182 | 0.79 | ADA (0.54) | ADA | |
| SCHEMBL7850108 | 0.77 | ADA (0.39) | ADA | |
| SCHEMBL6942809 | 0.77 | ADA (0.80) | ADA | |
| SCHEMBL7846509 | 0.75 | TP53 (0.41) | — | |
| SCHEMBL6941940 | 0.75 | ADA (0.80) | ADA | |
| SCHEMBL7845082 | 0.74 | ADA (0.38) | ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161429-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055155-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-09-21 | — | — | WO | disclosed |