Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 9/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 10/20 | 0.43 |
| ▸ | BCL2 | P10415 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846771 | 0.88 | ADA (0.51) | ADAMCL1BCL2 | |
| SCHEMBL7453033 | 0.76 | CTSG (0.44) | ADA | |
| SCHEMBL7848612 | 0.75 | ADA (0.60) | ADA | |
| SCHEMBL6938142 | 0.74 | ADA (1.00) | ADA | |
| SCHEMBL7837035 | 0.74 | ADA (0.59) | ADA | |
| SCHEMBL6935884 | 0.71 | ADA (1.00) | ADA | |
| SCHEMBL6938150 | 0.69 | ADA (0.78) | ADAMCL1 | |
| SCHEMBL7838799 | 0.68 | MTNR1A (0.41) | PPARGPPARA | |
| SCHEMBL7835522 | 0.68 | PDE5A (0.38) | — | |
| SCHEMBL7453024 | 0.67 | MMP13 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161429-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055155-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-09-21 | — | — | WO | disclosed |