Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | GABRP | O00591 | 1/20 | 0.61 |
| ▸ | GABRD | O14764 | 1/20 | 0.61 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.61 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.61 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.61 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.61 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.61 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.61 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.61 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.61 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.61 |
| ▸ | GABRE | P78334 | 1/20 | 0.61 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851164 | 0.89 | MEN1 (0.71) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27333775 | 0.88 | LMNA (1.00) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7854116 | 0.88 | LMNA (0.62) | LMNAPOLBMEN1KMT2AMAPT | |
| SCHEMBL7848175 | 0.87 | POLB (0.67) | LMNAPOLBMEN1KMT2AMAPT | |
| SCHEMBL7850581 | 0.85 | KMT2A (0.65) | LMNAPOLBMEN1KMT2AMAPT | |
| SCHEMBL7853106 | 0.85 | MAPT (0.66) | LMNAPOLBMEN1KMT2AMAPT | |
| SCHEMBL7855831 | 0.85 | POLB (0.64) | LMNAPOLBMEN1KMT2AMAPT | |
| SCHEMBL7849085 | 0.84 | MEN1 (0.87) | LMNAPOLBMEN1KMT2AMAPT | |
| SCHEMBL7856952 | 0.84 | KMT2A (0.68) | LMNAPOLBMEN1KMT2AMAPT | |
| SCHEMBL7838803 | 0.84 | LMNA (0.76) | LMNAPOLBMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140914-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037462-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2000-06-29 | — | — | WO | disclosed |