Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | RECQL | P46063 | 1/20 | 0.74 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.61 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MC4R | P32245 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NMBR | P28336 | 1/20 | 0.51 |
| ▸ | MC5R | P33032 | 1/20 | 0.49 |
| ▸ | MC3R | P41968 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847683 | 0.92 | HPGD (0.79) | HPGDHTTRECQLBCHEACHE | |
| SCHEMBL14261307 | 0.85 | HPGD (0.68) | HPGDHTTRECQLMTNR1ABCHE | |
| SCHEMBL7849079 | 0.82 | HPGD (0.93) | HPGDHTTRECQLBCHEACHE | |
| SCHEMBL7851490 | 0.82 | HTT (0.88) | HPGDHTTRECQLMTNR1ABCHE | |
| SCHEMBL7846847 | 0.82 | HPGD (0.67) | HPGDHTTRECQLBCHEACHE | |
| SCHEMBL14261162 | 0.81 | HPGD (0.61) | HPGDHTTRECQLRAB9AALDH1A1 | |
| SCHEMBL9086321 | 0.81 | MC4R (0.52) | HPGDHTTRECQLMTNR1AMTNR1B | |
| SCHEMBL9085410 | 0.80 | NMBR (0.48) | HPGDHTTRECQLALDH1A1MC4R | |
| SCHEMBL9373877 | 0.77 | NMBR (0.59) | HPGDHTTRECQLMTNR1AMTNR1B | |
| SCHEMBL9731275 | 0.77 | MTNR1A (1.00) | MTNR1AMTNR1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140914-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037462-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2000-06-29 | — | — | WO | disclosed |