Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 4/20 | 0.32 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7841969 | 0.82 | MAPT (0.38) | ADORA2AADORA1MAPTRXFP1POLB | |
| SCHEMBL6699653 | 0.74 | MEN1 (0.41) | MAPTRXFP1LMNATP53 | |
| SCHEMBL6701229 | 0.72 | MAPT (0.48) | MAPTRXFP1POLBLMNATP53 | |
| SCHEMBL6198743 | 0.71 | EGLN1 (0.35) | — | |
| SCHEMBL6693517 | 0.71 | MEN1 (0.42) | MAPTRXFP1LMNA | |
| SCHEMBL6199424 | 0.71 | EGLN1 (0.35) | — | |
| SCHEMBL6200529 | 0.70 | NR3C1 (0.33) | LMNA | |
| SCHEMBL6200835 | 0.69 | NR3C1 (0.33) | LMNA | |
| SCHEMBL6699650 | 0.69 | MEN1 (0.42) | MAPTRXFP1LMNATP53 | |
| SCHEMBL6697945 | 0.67 | MEN1 (0.43) | MAPTRXFP1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140850-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040561-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |