Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29371285 | 0.93 | TACR1 (1.00) | TACR1 | |
| SCHEMBL7918701 | 0.93 | TACR1 (1.00) | TACR1 | |
| SCHEMBL7918704 | 0.93 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8189477 | 0.92 | TACR1 (0.88) | TACR1 | |
| SCHEMBL9275375 | 0.92 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8189473 | 0.92 | TACR1 (0.88) | TACR1 | |
| SCHEMBL9275371 | 0.92 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8200980 | 0.92 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8200979 | 0.92 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8197471 | 0.89 | TACR1 (1.00) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258800-B1 | Prodrugs of benzofuranylethyl carbamate NK1 antagonists | WARNER-LAMBERT COMPANY | 2001-07-10 | — | — | US | disclosed |
| EP-1075472-A1 | PRODRUGS OF BENZOFURANYLMETHYL CARBAMATE NK 1? ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2001-02-14 | — | — | EP | disclosed |
| WO-1999052903-A1 | PRODRUGS OF BENZOFURANYLMETHYL CARBAMATE NK1 ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1999-10-21 | — | — | WO | disclosed |