Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.56 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.43 |
| ▸ | CALML3 | P27482 | 5/20 | 0.39 |
| ▸ | F10 | P00742 | 6/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SDHA | P31040 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843707 | 0.82 | MAOA (0.51) | MAOACYP2E1CALML3F10MAOB | |
| SCHEMBL6762702 | 0.81 | MAOA (0.57) | MAOACYP2E1CALML3F10 | |
| SCHEMBL7844473 | 0.80 | MAOA (0.46) | MAOACYP2E1F10 | |
| SCHEMBL3323196 | 0.80 | MAOA (0.79) | MAOACYP2E1CALML3MAOBLMNA | |
| SCHEMBL3323187 | 0.80 | MAOA (0.79) | MAOACYP2E1CALML3MAOBLMNA | |
| SCHEMBL3323189 | 0.80 | MAOA (0.79) | MAOACYP2E1CALML3MAOBLMNA | |
| SCHEMBL7846614 | 0.79 | MAOA (0.50) | MAOACYP2E1CALML3F10MAOB | |
| SCHEMBL7855134 | 0.78 | MAOA (0.51) | MAOACYP2E1CALML3F10MAOB | |
| SCHEMBL8556620 | 0.76 | MAOA (0.62) | MAOACALML3F10MAOBLMNA | |
| SCHEMBL7837804 | 0.76 | MAOA (0.38) | MAOACALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121358-A1 | HETEROCYCLYLAMINOMETHYLOXAZOLIDINONES AS ANTIBACTERIALS | AstraZeneca AB (SE) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000021960-A1 | HETEROCYCLYL AMINO METHYLOXA ZOLIDINONES AS ANTIBACTERIALS | ASTRAZENECA AB (SE) | 2000-04-20 | — | — | WO | disclosed |