Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 7/20 | 0.66 |
| ▸ | HTR1B | P28222 | 6/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.47 |
| ▸ | HTR1A | P08908 | 5/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91364 | 0.81 | HTR2A (0.63) | HTR1DHTR1BSLC6A4HTR1AHTR2A | |
| SCHEMBL22643951 | 0.81 | HTR1D (0.75) | HTR1DHTR1BHTR1AHTR2AMPO | |
| SCHEMBL13962815 | 0.80 | SLC6A4 (0.66) | HTR1DHTR1BSLC6A4HTR1AHTR2A | |
| SCHEMBL13962824 | 0.80 | SLC6A4 (0.66) | HTR1DHTR1BSLC6A4HTR1AHTR2A | |
| SCHEMBL2540516 | 0.80 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR2AHTR2C | |
| SCHEMBL7755853 | 0.80 | HTR1D (0.73) | HTR1DHTR1BSLC6A4HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL7816441 | 0.78 | HTR1D (0.97) | HTR1DHTR1BHTR1AHTR2AHTR2C | |
| SCHEMBL25903380 | 0.77 | HTR1D (0.69) | HTR1DHTR1BHTR1AHTR2AHTR2C | |
| SCHEMBL22643883 | 0.76 | HTR1D (0.68) | HTR1DHTR1BSLC6A4HTR1AHTR2A | |
| SCHEMBL8243669 | 0.76 | SLC6A4 (0.62) | HTR1DHTR1BSLC6A4HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129538-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |