SCHEMBL7847880

SCHEMBL7847880

Cc1c(CN(C(=O)O)C(C)(C)C)ccc2nc(N[C@@H](C=O)NC(C)CN3CCN(C)CC3)oc(=O)c12

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ELANE P08246 16/20 0.36
CTRB1 P17538 6/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6528361 0.84 CTRB1 (0.36) ELANECTRB1
SCHEMBL6528359 0.84 CTRB1 (0.36) ELANECTRB1
SCHEMBL7847884 0.81 ELANE (0.37) ELANECTRB1
SCHEMBL7847875 0.77 CTRB1 (0.33) ELANECTRB1
SCHEMBL6504856 0.77 CTRB1 (0.47) ELANECTRB1
SCHEMBL6503648 0.75 ELANE (0.61) ELANECTRB1
SCHEMBL7656409 0.75 CTRB1 (0.38) ELANECTRB1
SCHEMBL6504392 0.72 CTRB1 (0.44) ELANECTRB1
SCHEMBL6504857 0.72 ELANE (0.42) ELANECTRB1
SCHEMBL7152561 0.71 ELANE (0.44) ELANECTRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0828721-B1 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS SEARLE & CO (US) 2001-11-14 EP disclosed