Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 16/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 14/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.42 |
| ▸ | OGFRL1 | Q5TC84 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL7091412 | 0.91 | OPRM1 (0.44) | OPRM1OPRL1OPRK1OPRD1OGFRL1 | |
| Ammonia Solution, Strong SCHEMBL7091921 | 0.91 | OPRM1 (0.44) | OPRM1OPRL1OPRK1OPRD1OGFRL1 | |
| Ammonia Solution, Strong SCHEMBL7093777 | 0.90 | OPRM1 (0.45) | OPRM1OPRL1OPRK1OPRD1OGFRL1 | |
| Ammonia Solution, Strong SCHEMBL7095859 | 0.87 | OPRM1 (0.47) | OPRM1OPRL1OPRK1OPRD1OGFRL1 | |
| SCHEMBL7094878 | 0.81 | OPRM1 (0.45) | OPRM1OPRL1OPRK1OPRD1OGFRL1 | |
| SCHEMBL7091605 | 0.81 | TP53 (0.53) | OPRM1OPRL1OPRK1OPRD1OGFRL1 | |
| Ammonia Solution, Strong SCHEMBL7094452 | 0.81 | TP53 (0.48) | OPRM1OPRL1OPRK1OPRD1OGFRL1 | |
| SCHEMBL7091288 | 0.78 | OPRM1 (0.43) | OPRM1OPRL1OPRK1OPRD1OGFRL1 | |
| SCHEMBL7094475 | 0.77 | OPRM1 (0.49) | OPRM1OPRL1OPRK1OPRD1OGFRL1 | |
| SCHEMBL7095434 | 0.77 | OPRM1 (0.49) | OPRM1OPRL1OPRK1OPRD1OGFRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102762-A2 | 2-SUBSTITUTED-1-PIPERIDYL BENZIMIDAZOLE COMPOUNDS AS ORL1-RECEPTOR AGONISTS | PFIZER INC. (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000008013-A2 | 2-SUBSTITUTED-1-PIPERIDYL BENZIMIDAZOLE COMPOUNDS AS ORL1-RECEPTOR AGONISTS | PFIZER PHARMACEUTICALS INC. (JP) | 2000-02-17 | — | — | WO | disclosed |