Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 10/20 | 0.47 |
| ▸ | PTGIR | P43119 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4188958 | 0.92 | PTGS2 (0.68) | PTGS2PTGS1 | |
| SCHEMBL4184282 | 0.91 | PTGS2 (0.77) | PTGS2PTGS1 | |
| SCHEMBL4188762 | 0.82 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL4199071 | 0.81 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL4180376 | 0.80 | PTGS2 (0.82) | PTGS2PTGS1 | |
| SCHEMBL4194365 | 0.80 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL4180640 | 0.80 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL6601032 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7526467 | 0.79 | PTGS2 (0.91) | PTGS2PTGS1 | |
| SCHEMBL4190051 | 0.79 | PTGS2 (0.72) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124804-A1 | PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-08-22 | — | — | EP | claimed |
| WO-2000024719-A1 | PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2000-05-04 | — | — | WO | claimed |